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The series "Education for Health and Well-being for Indigenous Populations" (2019) and the "Javari Series: Preventive Education for STD/HIV/AIDS and ViralHepatitis of the Javari Valley" (2012) are prime examples of UNESCO’s efforts. Produced for Indigenous Peoples in the Amazonas region, specifically in the Vale do Javari, Alto Solimoes, these materials comprise 8 publications and 24 videos designed to assist indigenous schoolteachers in preventive health actions against sexually transmitted infections, HIV, viral hepatitis, COVID-19, malaria and tuberculosis. 

What sets these materials apart is their provision of content in the mother tongue of the Indigenous Peoples, facilitating better engagement with diverse age groups, genders and educational levels among indigenous students. Furthermore, they offer support for indigenous healthcare practitioners, including shamans, healers and midwives, thus empowering indigenous communities to advocate for the effective policies regarding education and health. 

All materials are developed through a participatory and multicultural approach so that indigenous knowledge and beliefs are respected and integrated. Anthropological validation from the indigenous groups ensures alignment with their perspectives and needs.

Responding to requests from indigenous leaders, publications have been developed in languages including Kanamari, Marubo, Matis and Mayoruna, addressing specific health concerns like HIV and other sexually transmitted infections (STIs). 

Since 2021, the project has expanded its reach to include other regions, engaging with diverse Indigenous Peoples such as , ,  and , including migrant indigenous populations from Venezuela now residing in Brazil. This expansion underscores the project's commitment to adaptability and inclusivity.                                                                                

Despite internet accessibility challenges, the project has attracted significant views on platforms like YouTube, particularly among populations like the Warao. The printed materials were carefully crafted on waterproof paper, considering their use in indigenous schools and by indigenous health workers, often operating in outdoor settings. 

Looking ahead, UNESCO Brazil plans to publish educational materials for ethnic groups like Desana, Gamella, Guajajara, Kaa'por, Tukano, Yalapiti, and Kamayura in 2024. In cases where only a single language speaker is identified, materials are designed not only for educational support but also to promote the use of the mother tongue within the community. 

UNESCO’s collaboration with local, regional and national governments, along with strategic partners, continues to expand the impact of the initiative. Indigenous Peoples themselves highly request these efforts, recognizing the importance of aligning their cultures sustainability with improved health education and prevention measures.